Synectic Corporation was established in 1988 to focus on custom synthesis of small-volume organic chemicals, mostly for the pharmaceutical industry.
Synectic specializes in custom manufacture of organic compounds in the gram to multi-kilo range.
Inquiries are evaluated promptly, and price ideas are normally provided within a few days of receipt, followed by a firm proposal shortly thereafter.
Synectic has considerable expertise in the synthesis of Organoselenium compounds and in the synthesis of heterocycles, such as Thiazole and substituted Thiazoles, substituted Indoles and derivatives, substituted Imidazoles, Benzimidazoles, and Imidazolines, substituted Thiobarbituric acids, Isatins, Oxindoles Indazoles, Quinolines, Pyrimidines and Selenophenes.
Synectic is also working in the areas of Carbohydrates and Oligosacharides, Amino Acids (racemic and chiral), and chiral compounds by both asymmetric synthesis and by resolution.
New processes include catalytic methods for production of Ketones and Ketone derivatives.
Reactions performed include, but are not limited to:
- Reduction:
- Lithium Aluminum Hydride
- Sodium Borohydride
- Chiral Reductions
- Catalytic Reductions
- Sodium bis (2-Methoxyethoxy) Aluminum Hydride (Vitride)
- Reductive Alkylation
- Oxidation:
- Hydrogen Peroxide
- Selenium Dioxide
- tert-Butyl Hydroperoxide
- Catalytic Methods
- Sodium Hypochlorite
- Molecular Oxygen
- Sodium Perborate
- Fluorination and Halogen Exchange
- Grignard Reaction
- Pressure Reactions
- Photochemical Reactions
- Organoselenium Chemistry
- Suzuki Coupling
- Hot-tube Reactions (to 600° C.)
- Halogenation
- Diazatization and Hydrolysis
- Acylation and Alkylation
- Condensations, Ring Closures, etc.
- Enzymatic Reactions
- Skraup Quinoline Synthesis
- Ammonolysis and Amination
- Pyrolysis /High Temperature Reactions
- Amino Acid Synthesis and Resolution
- Fischer Indole Synthesis
- Reissert Indole Synthesis
- Heck Reaction
- Asymmetric Synthesis
- Malonic Ester Synthesis
- Phase Transfer Catalysis
- Hinsberg Oxindole Synthesis
- Chiral Resolutions
- Alkenes by Dehydration of Alcohols